The fastest and most comfortable way to get from Rome to Milan is by high-speed train service. Alternatively, you can take a regional train or bus for a lower price. A high-speed train ride will take you to the destination in 2 hours 55 minutes with the one-way ticket cost starting from 20 euro. Milan is 358 miles north of Rome. The distance between the two cities by car is 479 km. Moreover, Italy’s largest international airports are in Rome and Milan, so if you need to get between these cities quickly, many flights are offered daily.

Let’s consider all transport options:

By Train

Getting from Rome to Milan by fast train is the most convenient option. You can reach Milan in 2 hours 55 minutes. However, many regional trains have lower prices for tickets, but the journey will be longer. Nevertheless, it is one of the best options for day trips from Rome.

• The best train operator is ItaloTreno for its high-class service and all amenities to travel with comfort. If you wonder how to go from Rome to Milan, I recommend you choose this option.

As shown in the screenshot, the cost varies according to the time of departure and class. “Prima” means the first class dedicated to travelers seeking journeys with maximum comfort. The “Smart” option gives the best deals, but don’t worry; its comfort level is still amazing.

Also, Trenitalia is a good alternative way to reach Florence from the Eternal City. However, the website has a bit more complicated registration procedure, and sometimes there are faults. Trains from this service depart once in an hour, and I suggest you take high-speed trains Frecciarossa.

How Long and How Much?

Since getting to Milan from Rome by train is the best and fastest way, it is also the most expensive one. As mentioned above, the one-way ticket price ticket starts from 20 euro and duration is almost 3 hours to reach the destination. Moreover, do not forget to plan your journey to the station in Rome from which you will have a train to Milan. Usually, trains depart from Roma Termini, and it is the central station of Rome. Therefore, if you live nearby any Roman train station, you will easily reach Roma Termini. Also, many buses will get you to this station, but I recommend using trains or metro not to be late.

By Bus

FlixBus company is one of the most popular bus services for budget travelers who want to visit Milan from Rome since it is the cheapest kind of transportation to travel. Buses depart from Rome Tiburtina Station once in 1-2 hours. You can book tickets online or buy them directly at the bus station. The journey will take from 7 to 11 hours. Bus fares start from 18.99 euro.

By Car

For getting from Rome to Milan by car, you need the A1 autostrada, which runs between these two cities, and you can reach Milan in 5.5 hours. I recommend using this option for a longer trip version with a visit to other cities on your way. For instance, you can visit Parma, Bologna, Florence, and Siena.

By Plane

Since two main Italian international airports are located in Rome and Milan, getting from one city to another by plane is also easy and accessible. However, this option is the most expensive one if you will not buy tickets in advance. Milan has two airports: the larger is Milan Malpensa with international flights and the smaller Milan Linate with flights mainly from other parts of Italy and Europe. In addition, some buses connect both airports with Milan central station (Milano Centrale) and trains that run from Milano Malpensa to the central station.

Things to Do in Milan

1. Go for a night out in the Navigli district
2. Visit one of several famous Italian outlets
3. Go out for Italian aperitivo in the evening
4. Visit The Last Supper by Leonardo Da Vinci
5. Rent a bike and ride down the canals
6. Admire the queue to first Starbucks in Italy ever, which was opened in Milan in fall, 2018
7. Take a photo near the Duomo di Milano and, of course, go inside it
8. Go shopping at the Grand Galleria Vittorio Emanuele II
9. The experience nightlife of Milan in one of its nightclubs
10. Visit Castello Sforzesco, which is a 15th-century castle with a central location in Milan. It is set in extensive grounds and garden

Where to Stay in Milan

There are many options where to stay in Milan on any budget. Since the transportation system is very well developed in the city, you can also consider options outside the city center.

Queen Hostel

Queen Hostel is set in 1 minute from Milan Cathedral. There is free WiFi available throughout the property. Moreover, rooms come with a shared bathroom. The atmosphere is really nice and friendly.

• Price per night for 1 person starts from 25 euro

Starhotels Business Palace

Starhotels Business Palace is located 50m from Porto di Mare Metro Station and is a 10-minute walk from Rogoredo Train Station. There is a gym with panoramic city views, free WiFi throughout, and a spacious outdoor area. All rooms are beautiful and clean.

• Price per night for 2 people starts from 70 euro

The Yard Milano

The Yard Milano Hotel is located in the Navigli area, with many bars and restaurants. This stylish design hotel is decorated in a sports theme. There are excellent breakfasts, friendly staff and it is definitely worth considering staying there.

• Price per night for 2 people starts from 300 euro

The Square Milano Duomo

The Square Hotel Milano Duomo is literally a 5-minute walk from the Duomo and La Scala Theater. There are spacious and clean rooms and excellent breakfasts with champagne. On the roof of the hotel, there is a restaurant with stunning views of the city—the perfect 4-stars option.

• Price per night for 2 people starts from 250 euro

Armani Hotel Milano

Armani Hotel Milano is the signature hotel of the Armani family. It is located in the Milan quarter of Fashion Square. After a day of crazy shopping, hotel guests can rejuvenate at the Turkish bath or sauna. The hotel has a Michelin restaurant specializing in dishes from the Lombardy region.

• Price per night for 2 people starts from 700 euro

The TownHouse Galleria

The TownHouse Galleria is located right inside the most famous shopping gallery in the world. The hotel is recommended for special occasions – honeymoon, birthday present, marriage proposal. Service, location, food, rooms – everything is excellent.

• The price per night for 2 people starts from 400 euro.